Polymorphisms of the endothelial nitric oxide synthase (NOS3) gene in preeclampsia: a candidate-gene association study

Table 3 Association results.

SNP	Genetic contrast	OR (95% CI)	p-value	OR_adjusted (95% CI)
4b/a	Allele contrast (b vs. a)	0.78 (0.50-1.21)	0.27
	Recessive model	0.81 (0.49-1.36)	0.43	0.81 (0.48-1.35)
	Dominant model	0.24 (0.03-1.97)	0.18	0.24 (0.03-1.97)
T-786C	Allele contrast (C vs. T)	0.94 (0.66-1.34)	0.73
	Recessive model	0.83 (0.41-1.17)	0.59	0.81 (0.40-1.63)
	Dominant model	0.97 (0.59-1.62)	0.91	0.93 (0.56-1.56)
G894T	Allele contrast (T vs. G)	0.91 (0.65-1.30)	0.60
	Recessive model	1.27 (0.65-2.49)	0.49	1.25 (0.63-2.46)
	Dominant model	0.74 (0.45-1.21)	0.23	0.72 (0.439-1.19)

Odds Ratio (OR) and the corresponding 95% Confidence Intervals (CIs) for testing the association between preeclampsia and NOS3 4b/a, T-786C and G894T polymorphisms for the allele contrast, the dominant and recessive models. The ORs adjusted for age are also shown.

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