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Table 4 Risk of adverse perinatal outcomes in relation to alcohol intake peri-conceptionally

From: Prevalence, predictors and perinatal outcomes of peri-conceptional alcohol exposure - retrospective cohort study in an urban obstetric population in Ireland

Alcohol intakei Low (0 - 5 units) Unadjusted OR (95% CI) Low (0-5 units) Adjusted ORii (95% CI) Moderate (6 - 20 units) Unadjusted OR (95% CI) Moderate (6-20 units) Adjusted ORii (95% CI) High (>20 units) Unadjusted OR (95% CI) High (>20 units) Adjusted ORii (95% CI)
Preterm birth <37 weeks 0.72 (0.66-0.78) 0.77 (0.69-0.85) 0.70 (0.61-0.81) 0.71 (0.60-0.83) 1.70 (0.55-3.05) 1.00 (0.53-1.87)
Very preterm birth <32 wks 0.76 (0.63-0.92) 0.88 (0.70-1.11) 0.82 (0.61-1.10) 0.95 (0.66-1.37) 3.93 (1.70-9.06)* 3.15 (1.26-7.88)*
Low birth weight <2500 g 0.75 (0.69-0.83) 0.69 (0.61-0.78) 0.82 (0.71-0.95) 0.71 (0.58-0.87) 2.09 (1.14-3.83)* 1.15 (0.60-2.22)
Birth weight <10th centile 0.97 (0.92-1.03) 1.01 (0.96-1.06) 1.06 (0.98-1.17) 1.00 (0.92-1.09) 2.82 (1.88-4.23)* 1.44 (0.91-2.25)
Perinatal death 0.86 (0.69-1.08) 0.65 (0.47-0.90) 0.93 (0.65-1.32) 0.72 (0.44-1.18) 2.11 (0.51-8.65) 1.56 (0.33-7.44)
Apgar score <7 at 5 minutes 0.77 (0.64-0.92) 0.67 (0.53-0.85) 0.88 (0.66-1.17) 0.62 (0.42-0.92) 1.32 (0.32-5.41) 1.09 (0.25-4.73)
Admission to neonatal unit 0.89 (0.84-0.95) 0.84 (0.78-0.90) 0.95 (0.87-1.03) 0.83 (0.73-0.93) 1.37 (0.86-2.17) 0.91 (0.56-1.49)
Congenital abnormality (any) 0.85 (0.76-1.24) 1.01 (0.71-1.44) 1.01 (0.85-1.21) 1.01 (0.82-1.27) 0.81 (0.26-2.56) 0.56 (0.17-1.88)
  1. i Reference category for all comparisons - alcohol intake response "Never"
  2. ii adjusted for maternal age, single marital status, socio-economic status, nationality, private health insurance, nulliparity, unplanned pregnancy, late booking, smoking and history of illicit drug use
  3. * p < 0.05