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Table 4 Risk of adverse perinatal outcomes in relation to alcohol intake peri-conceptionally

From: Prevalence, predictors and perinatal outcomes of peri-conceptional alcohol exposure - retrospective cohort study in an urban obstetric population in Ireland

Alcohol intakei

Low

(0 - 5 units)

Unadjusted OR

(95% CI)

Low

(0-5 units)

Adjusted ORii

(95% CI)

Moderate

(6 - 20 units)

Unadjusted OR

(95% CI)

Moderate

(6-20 units)

Adjusted ORii

(95% CI)

High

(>20 units)

Unadjusted OR

(95% CI)

High

(>20 units)

Adjusted ORii

(95% CI)

Preterm birth <37 weeks

0.72 (0.66-0.78)

0.77 (0.69-0.85)

0.70 (0.61-0.81)

0.71 (0.60-0.83)

1.70 (0.55-3.05)

1.00 (0.53-1.87)

Very preterm birth <32 wks

0.76 (0.63-0.92)

0.88 (0.70-1.11)

0.82 (0.61-1.10)

0.95 (0.66-1.37)

3.93 (1.70-9.06)*

3.15 (1.26-7.88)*

Low birth weight <2500 g

0.75 (0.69-0.83)

0.69 (0.61-0.78)

0.82 (0.71-0.95)

0.71 (0.58-0.87)

2.09 (1.14-3.83)*

1.15 (0.60-2.22)

Birth weight <10th centile

0.97 (0.92-1.03)

1.01 (0.96-1.06)

1.06 (0.98-1.17)

1.00 (0.92-1.09)

2.82 (1.88-4.23)*

1.44 (0.91-2.25)

Perinatal death

0.86 (0.69-1.08)

0.65 (0.47-0.90)

0.93 (0.65-1.32)

0.72 (0.44-1.18)

2.11 (0.51-8.65)

1.56 (0.33-7.44)

Apgar score <7 at 5 minutes

0.77 (0.64-0.92)

0.67 (0.53-0.85)

0.88 (0.66-1.17)

0.62 (0.42-0.92)

1.32 (0.32-5.41)

1.09 (0.25-4.73)

Admission to neonatal unit

0.89 (0.84-0.95)

0.84 (0.78-0.90)

0.95 (0.87-1.03)

0.83 (0.73-0.93)

1.37 (0.86-2.17)

0.91 (0.56-1.49)

Congenital abnormality (any)

0.85 (0.76-1.24)

1.01 (0.71-1.44)

1.01 (0.85-1.21)

1.01 (0.82-1.27)

0.81 (0.26-2.56)

0.56 (0.17-1.88)

  1. i Reference category for all comparisons - alcohol intake response "Never"
  2. ii adjusted for maternal age, single marital status, socio-economic status, nationality, private health insurance, nulliparity, unplanned pregnancy, late booking, smoking and history of illicit drug use
  3. * p < 0.05