Pre-intervention N = 607 | NASG N = 835 | pvalue | |
---|---|---|---|
Study sites | |||
Egypt (2 referral hospitals) | 432 | 558 | -- |
Nigeria (4 referral hospitals) | 175 | 277 | -- |
Demographic characteristics | |||
Age: Mean years of age (SD) | 29.0 (6.4) | 29.3 (6.2) | 0.27 |
Median age (IQR) | 28 (25-33) | 29 (25-35) | -- |
Parity: Mean live births (SD) | 3.2 (2.8) | 3.3 (2.8) | -- |
Median parity (IQR) | 2 (1-5) | 3 (1-5) | 0.18 |
Pregnancy duration: Mean weeks (SD)* | 37.0 (4.1) | 37.4 (3.6) | -- |
Median weeks (IQR) | 38 (36-40) | 38 (36-40) | 0.18 |
Primary definitive diagnosis | |||
Uterine atony | 190 (33.0) | 319 (38.2) | 0.007 |
Ectopic pregnancy | 95 (15.7) | 85 (10.2) | 0.002 |
Complications of abortion | 45 (7.4) | 93 (11.1) | 0.02 |
Abruption of placenta | 79 (13.0) | 98 (11.7) | 0.47 |
Vaginal, cervical or genital lacerations | 25 (4.1) | 65 (7.8) | 0.004 |
Retained placenta or tissue | 71 (11.7) | 83 (9.9) | 0.29 |
Ruptured uterus | 46 (7.6) | 32 (3.8) | 0.002 |
Placenta previa | 40 (6.6) | 31 (3.7) | 0.01 |
Placenta accrete | 6 (1.0) | 9 (1.1) | 1.000√ |
Molar pregnancy | 7 (1.2) | 11 (1.3) | 1.000√ |
Condition on study entry | |||
Where hemorrhage began | <0.001 | ||
Transferred in bleeding | 382 (72.9) | 333 (56.4) | |
Began bleeding in hospital | 142 (27.1) | 258 (43.6) | |
Estimated revealed blood loss at study entry+ | |||
Mean mL (SD) | 1210.0 (507.7) | 1327.5 (480.7) | -- |
Median mL (IQR) | 1000 (1000-1500) | 1200 (1000-1500) | <.0001 |
Women with MAP < 60 or non-palpable BP‡ | 181 (29.9) | 321 (38.5) | 0.001 |