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Table 1 Distribution of known mutations in the Factor V gene

From: APCR, factor V gene known and novel SNPs and adverse pregnancy outcomes in an Irish cohort of pregnant women

APCR with Classic Coatest® test only n = 105

Frequency %

n

mutation

15

16

ht (H) R2

85

89

no mutations

APCR with Classic and Modified Coatest ® test n = 34

Frequency %

n

mutation

85

29

hz FV Leiden

3

1

hz Cambridge* 1

3

1

hz (H) R2

14

4

no mutations

APCR with Modified Coatest ® test only n = 1

Frequency %

n

mutation

100

1* 2

no mutations

  1. Abbreviations: (n) number of subjects, (ht) heterozygotes, (hom) homozygotes, (H) haplotype.
  2. * 1 n = 1 had hz Cambridge and FVL mutations simultaneously.
  3. * 2 Subject was not included in the scanning for novel SNPs as insufficient DNA sample was available for the study.