Table 2 Antihypertensive therapy among singleton pregnant women with either all forms of hypertension or hypertension before 20 weeks gestation
No. (%) | ||
|---|---|---|
Drug use | Women with all forms of hypertension (n = 1948) | Women with hypertension before 20 weeks gestation (n = 583) |
By number of drugs | ||
None | 980 (50.3) | 247 (42.4) |
Single agent | 569 (29.2) | 207 (35.5) |
Multiple agents | 399 (20.5) | 129 (22.1) |
Total | 1948 (100.0) | 583 (100.0) |
By drug class | ||
i) Beta-blockers * | ||
Atenolol | 743 (94.9) | 236 (92.9) |
Labetolol | 29 (3.7) | 10 (3.9) |
Propranolol | 8 (1.0) | 6 (2.4) |
Acebutalol | 3 (0.4) | 2 (0.8) |
Total | 783 (100.0) | 254 (100.0) |
ii) Non-beta-blockers * | ||
Nifedipine | 301 (47.7) | 93 (38.9) |
Methyldopa | 175 (27.7) | 91 (38.1) |
Hydralazine | 129 (20.4) | 30 (12.6) |
Enalapril or captopril | 19 (3.0) | 19 (7.9) |
Hydrochlorothiazide | 5 (0.8) | 5 (2.1) |
Furosemide | 2 (0.3) | 1 (0.4) |
Total | 631 (100.0) | 239 (100.0) |