Volume 7 Supplement 1

Proceedings of the First and Second European Workshops on Preterm Labour of the Special Non-Invasive Advances in Fetal and Neonatal Evaluation (SAFE) Network of Excellence

Proceedings

Edited by Jörg Strutwolf, Universitat Rovira i Virgili, Tarragona, Spain and Andrés López Bernal, University of Bristol, Bristol, UK

The conferences were organized with support from the Special Non-invasive Advances in Fetal and Neonatal Evaluation (SAFE) Networkof Excellence (European Commission, LSHB-CT-2004-503243). Publication costs were covered by Ferring Pharmaceuticals, PerkinElmer and Merck-Seron

Special Non-Invasive Advances in Fetal and Neonatal Evaluation Network of Excellence, First and Second European Workshops on Preterm Labour. Go to conference site.

Tarragona, Spain

21-22 September 2006 and 22 June 2005

  1. Proceedings

    Overview. Preterm labour: mechanisms and management

    Preterm birth remains a major cause of perinatal mortality and long term handicap in surviving infants. This is one of the most important clinical problems in Europe and across the world. While some preterm bi...

    Andrés López Bernal

    BMC Pregnancy and Childbirth 2007 7(Suppl 1):S2

    Published on: 1 June 2007

  2. Proceedings

    Towards understanding the myometrial physiome: approaches for the construction of a virtual physiological uterus

    Premature labour (PTL) is the single most significant factor contributing to neonatal morbidity in Europe with enormous attendant healthcare and social costs. Consequently, it remains a major challenge to alle...

    Michael John Taggart, Andrew Blanks, Sanjay Kharche, Arun Holden, Bin Wang and Henggui Zhang

    BMC Pregnancy and Childbirth 2007 7(Suppl 1):S3

    Published on: 1 June 2007

  3. Proceedings

    Inflammatory pathways in the mechanism of parturition

    Increasing evidence suggests that parturition is an inflammatory process. In this brief overview, inflammatory events occurring in association with parturition, and the mechanism by which they may contribute t...

    Jane E Norman, Shrikant Bollapragada, Mei Yuan and Scott M Nelson

    BMC Pregnancy and Childbirth 2007 7(Suppl 1):S7

    Published on: 1 June 2007

  4. Proceedings

    A translational approach to studying preterm labour

    Preterm labour continues to be a major contributor to neonatal and infant morbidity. Recent data from the USA indicate that the number of preterm deliveries (including those associated with preterm labour) has...

    Rachel Marie Tribe

    BMC Pregnancy and Childbirth 2007 7(Suppl 1):S8

    Published on: 1 June 2007

  5. Proceedings

    Cyclic AMP signalling pathways in the regulation of uterine relaxation

    Studying the mechanism(s) of uterine relaxation is important and will be helpful in the prevention of obstetric difficulties such as preterm labour, which remains a major cause of perinatal mortality and morbi...

    Wei Yuan and Andrés López Bernal

    BMC Pregnancy and Childbirth 2007 7(Suppl 1):S10

    Published on: 1 June 2007

  6. Proceedings

    Protein kinase C and human uterine contractility

    Abnormalities in uterine contractility are thought to contribute to several clinical problems, including preterm labor. A better understanding of the mechanisms controlling uterine activity would make it possi...

    Isabelle Eude-Le Parco, Emmanuelle Dallot and Michelle Breuiller-Fouché

    BMC Pregnancy and Childbirth 2007 7(Suppl 1):S11

    Published on: 1 June 2007

  7. Proceedings

    PDE4 as a target in preterm labour

    Cyclic nucleotide phosphodiesterases (PDE) are the enzymes catalyzing the hydrolysis and inactivation of the second messengers, cAMP and cGMP. Eleven PDE families are described to date, and selective inhibitor...

    Céline Méhats, Thomas Schmitz, Stéphanie Oger, Roxane Hervé, Dominique Cabrol and Marie-Josèphe Leroy

    BMC Pregnancy and Childbirth 2007 7(Suppl 1):S12

    Published on: 1 June 2007

  8. Proceedings

    Is the beta3-adrenoceptor (ADRB3) a potential target for uterorelaxant drugs?

    The management of premature birth still remains unsatisfactory. Since the relative lack of efficiency and/or safety of current tocolytic agents have been highlighted, it is necessary to develop new uterorelaxa...

    Marc Bardou, Céline Rouget, Michèle Breuiller-Fouché, Catherine Loustalot, Emmanuel Naline, Paul Sagot, René Frydman, Esteban J Morcillo, Charles Advenier, Marie-Josèphe Leroy and John J Morrison

    BMC Pregnancy and Childbirth 2007 7(Suppl 1):S14

    Published on: 1 June 2007

  9. Proceedings

    Tocolytic effect of a selective FP receptor antagonist in rodent models reveals an innovative approach to the treatment of preterm labor

    Management of preterm labor by tocolysis remains an unmet medical need. Prostaglandins play a major role in regulation of uterine activity and in molecular mechanisms of human labor and parturition. There is s...

    André Chollet, Enrico Gillio Tos and Rocco Cirillo

    BMC Pregnancy and Childbirth 2007 7(Suppl 1):S16

    Published on: 1 June 2007

  10. Proceedings

    Clinical aspects of cervical insufficiency

    Fetal loss is a painful experience. A history of second or early third trimester fetal loss, after painless dilatation of the cervix, prolapse or rupture of the membranes, and expulsion of a live fetus despite...

    Frederik K Lotgering

    BMC Pregnancy and Childbirth 2007 7(Suppl 1):S17

    Published on: 1 June 2007