From: The maternal factors associated with infant low birth weight: an umbrella review
Evidence | Criteria | factors |
---|---|---|
Convincing evidence (Class I) | number of cases > 1000 p-value of the meta-analysis < 10− 6 I² < 50% 95% prediction interval excluding the null p-value of the egger test > 0.05 and p-value of the Ioannidis test > 0.05 | Crack/cocaine Infertility |
Highly suggestive (Class II) | number of cases > 1000 p-value of the meta-analysis < 10− 6 largest study with a statistically significant effect and class I criteria were not met | antenatal Care smoking |
Suggestive (Class III) | number of cases > 1000 p-value of the meta-analysis < 10− 3 and class I–II criteria not met | caffeine/coffee anemia Depression Periodontal disease |
Weak (Class IV) | p-value of the meta-analysis < 0.05 and class I–III criteria not met | heavy physical workload underweight heavy lifting alcohol hypothyroidism Hypertension |
Non-significant Associations (NS) | p-value of the meta-analysis > = 0.05 | overweight/obesity |