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Table 3 Neonatal outcomes in the untreated and treated GDM groups using the IADPSG and NICE criteria

From: Neonatal outcomes according to different glucose threshold values in gestational diabetes: a register-based study

 

Controls

IADPSG

   

NICE

   
  

Untreated

 

Treated

 

Untreated

 

Treated

 
   

pª

 

pb

 

pª

 

pb

N (%)

3031 (61.4)

509 (10.3)

 

1292 (26.2)

 

166 (3.4)

 

612 (12.4)

 

Composite adverse neonatal outcome, n (%)

279 (9.2)

51 (10.0)

0.564

287 (22.2)

 < 0.001

20 (12.0)

0.272

164 (26.8)

 < 0.001

Hypoglycaemia, n (%)

74 (2.4)

17 (3.3)

0.288

187 (14.5)

 < 0.001

6 (3.6)

0.439

106 (17.3)

 < 0.001

Hyperbilirubinaemia, n (%)

172 (5.7)

32 (6.3)

0.607

108 (8.4)

0.144

9 (5.4)

1.000

62 (10.1)

0.068

Birth trauma, n (%)

39 (1.3)

4 (0.8)

0.393

21 (1.6)

0.189

3 (1.8)

0.723

13 (2.1)

1.000

Perinatal mortality, n (%)

6 (0.2)

1 (0.2)

1.000

5 (0.4)

0.682

2 (1.2)

0.061

4 (0.7)

0.613

Birth weight, g, mean (SD)

3572.7 (525.7)

3632.9 (543.5)

0.017

3561.5 (562.3)

0.014

3499.9 (603.2)

0.130

3539.9 (623.5)

0.461

Birth weight < 2.5 kg, n (%)

89 (2.9)

18 (3.5)

0.483

49 (3.8)

0.890

9 (5.4)

0.098

34 (5.6)

1.000

Birth weight > 4.5 kg, n (%)

94 (3.1)

21 (4.1)

0.279

36 (2.8)

0.177

6 (3.6)

0.818

21 (3.4)

1.000

Birth weight SD score, mean (SD)

-0.047 (1.01)

0.12 (1.05)

 < 0.001

0.072 (1.08)

0.434

0.011 (1.05)

0.476

0.12 (1.19)

0.293

LGA, n (%)

267 (8.8)

65 (12.8)

0.005

147 (11.4)

0.417

22 (13.3)

0.069

82 (13.4)

1.000

Gestational age at delivery in weeks, mean (SD)

39.9 (1.57)

39.8 (1.60)

0.154

39.5 (1.81)

 < 0.001

39.5 (1.93)

0.002

39.2 (2.01)

0.185

Preterm birth < 37 weeks, n (%)

114 (3.8)

21 (4.1)

0.707

78 (6.0)

0.135

12 (7.2)

0.037

49 (8.0)

0.751

Neonatal respiratory distress syndrome, n (%)

15 (0.5)

3 (0.6)

1.000

9 (0.7)

1.000

1 (0.6)

1.000

5 (0.8)

0.293

Newborn discharge status aged 7 days, n (%)

 Home

2895 (95.5)

482 (94.7)

0.423

1195 (92.5)

0.099

152 (91.6)

0.025

547 (89.4)

0.470

 Hospitalised

130 (4.3)

25 (4.9)

0.558

91 (7.0)

0.110

11 (6.6)

0.170

61 (10.0)

0.227

 Hospitalisation in days, mean (SD)

3.1 (2.61)

3.2 (1.37)

0.514

3.3 (2.09)

0.157

3.3 (1.45)

0.425

3.5 (2.71)

0.315

  1. GDM Gestational diabetes mellitus
  2. IADPSG The International Association of Diabetes and Pregnancy Study Groups
  3. NICE The National Institute for Health and Care Excellence
  4. ªp-value between the GDM group and controls
  5. bp-value between the treated and untreated GDM groups
  6. SD Standard deviation
  7. The composite adverse neonatal outcome included hypoglycaemia, hyperbilirubinaemia, birth trauma or perinatal mortality
  8. Birth trauma included Erb’s palsy or clavicle fracture
  9. LGA Large for gestational age, defined as having a birth weight SD score > 90th percentile
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BMC Pregnancy and Childbirth

ISSN: 1471-2393

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