Table 3 Detailed information of significant differences in polar metabolites between vitamin D deficiency and sufficiency pregnant women
From: Targeted metabolomics profiling in pregnancy associated with vitamin D deficiency
mz | Name | Formula | Deficiency versus Sufficiency | Inadequacy versus Sufficiency | ||||
|---|---|---|---|---|---|---|---|---|
Fold change | P value | Fold change | P value | |||||
166.0858 | Phenylalanine | C9H11NO2 | -536.31 | 1.36E-02 | -744.05 | 1.70E-02 | ||
132.1016 | Leucine | C6H13NO2 | -398.83 | 1.39E-02 | -584.41 | 1.74E-02 | ||
205.0966 | Tryptophan | C11H12N2O2 | -152.61 | 1.37E-02 | -134.47 | 1.73E-02 | ||
182.0807 | Tyrosine | C9H11NO3 | -54.05 | 1.35E-02 | -46.28 | 1.73E-02 | ||
118.0859 | Valine | C5H11NO2 | -36.39 | 1.07E-02 | -32.15 | 1.40E-02 | ||
116.0705 | Proline | C5H9NO2 | -31.92 | 1.22E-02 | -29.07 | 1.57E-02 | ||
150.058 | Methionine | C5H11NO2S | -21.03 | 1.12E-02 | -16.03 | 1.57E-02 | ||
175.1184 | Arginine | C6H14N4O2 | -8.91 | 7.42E-03 | -8.29 | 1.05E-02 | ||
147.1124 | Lysine | C6H14N2O2 | -5.88 | 1.40E-02 | -7.31 | 1.34E-02 | ||
90.0552 | Alanine | C3H7NO2 | -5.79 | 3.95E-03 | -4.69 | 7.99E-03 | ||
209.0913 | L-Kynurenine | C10H12N2O3 | -4.21 | 1.44E-02 | -4.17 | 1.81E-02 | ||
221.0914 | 5-Hydroxy-L-tryptophan | C11H12N2O3 | -2.23 | 1.36E-02 | -1.65 | 1.54E-01 | ||
146.0809 | Allysine | C6H11NO3 | -1.80 | 5.31E-03 | -1.57 | 2.30E-02 | ||
165.0542 | Phenylpyruvate | C9H8O3 | -100.26 | 1.26E-02 | -131.10 | 1.56E-02 | ||
137.0455 | Hypoxanthine | C5H4N4O | -48.14 | 1.35E-02 | -59.90 | 1.64E-02 | ||
132.0762 | Creatine | C4H9N3O2 | -18.40 | 6.93E-03 | -28.54 | 7.54E-03 | ||
88.076 | 4-Aminobutyraldehyde | C5H9NO2 | -14.53 | 1.35E-03 | -16.05 | 1.77E-03 | ||
169.0491 | Homogentisate | C8H8O4 | -13.99 | 1.32E-02 | -14.21 | 1.65E-02 | ||
227.0783 | AFMU | C8H10N4O4 | -7.34 | 8.72E-03 | -7.83 | 1.06E-02 | ||
130.086 | L-Pipecolate | C6H11NO2 | -6.98 | 7.17E-03 | -4.85 | 1.68E-02 | ||
153.0655 | N1-Methyl-2/4-pyridone-5-carboxamide | C7H8N2O2 | -6.64 | 5.39E-03 | -6.85 | 6.97E-03 | ||
176.0701 | Indole-3-acetate | C10H9NO2 | -5.93 | 1.67E-03 | -6.66 | 1.52E-03 | ||
74.0606 | Aminoacetone | C3H7NO | -5.60 | 1.04E-03 | -3.22 | 3.09E-02 | ||
180.065 | Hippurate | C9H9NO3 | -4.27 | 2.42E-02 | -4.10 | 3.51E-02 | ||
175.1074 | N-Acetylornithine | C7H14N2O3 | -4.11 | 1.83E-02 | -4.63 | 1.64E-02 | ||
160.0753 | Indole-3-acetaldehyde | C10H9NO | -4.11 | 1.59E-02 | -3.58 | 2.61E-02 | ||
265.1169 | Formyl-N-acetyl-5-methoxykynurenamine | C13H16N2O4 | -3.70 | 4.16E-03 | -4.50 | 2.69E-03 | ||
123.0551 | Nicotinamide | C6H6N2O | -3.68 | 1.45E-02 | -3.45 | 2.16E-02 | ||
190.0492 | 1-Nitronaphthalene-5,6/7,8-oxide | C10H7NO3 | -2.97 | 3.44E-03 | -2.68 | 1.44E-02 | ||
139.0498 | Urocanate | C6H6N2O2 | -2.93 | 5.09E-03 | -3.68 | 5.23E-04 | ||
243.0618 | Uridine | C9H12N2O6 | 1.72 | 3.09E-02 | 1.49 | 1.67E-01 | ||
298.097 | Methylthioadenosine | C11H15N5O3S | 1.92 | 4.73E-02 | 1.66 | 8.33E-02 | ||
167.0199 | Urate | C5H4N4O3 | 1.86 | 4.17E-02 | 1.62 | 8.24E-02 | ||