Fig. 4

Fetal blood flow metrics as predictors of prior drug exposure and future perinatal mortality. A) Kaplan-Meier analysis of offspring survival rates across drug-exposed pregnancies. B) Pearson’s r correlations between ultrasound measures of cerebroplacental ratios and perinatal mortality among offspring and dams. C) Predictive capacity of cerebroplacental ratios to prior drug exposure or subsequent perinatal offspring mortality. Abbreviations: G = Gestational Day, VTI = Velocity-Time Integral, CPR = Cerebroplacental Ratio, ALC = Alcohol, CB = Cannabinoid, ALC + CB = Alcohol + Cannabinoid, N.S = statistically non-significant. Symbols: * indicates p < 0.05, ** indicates p < 0.01