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Fig. 1 | BMC Pregnancy and Childbirth

Fig. 1

From: Reduced fetal cerebral blood flow predicts perinatal mortality in a mouse model of prenatal alcohol and cannabinoid exposure

Fig. 1

Experimental outline and polysubstance exposure characterization. A) Experimental timeline for prenatal drug exposure and ultrasound imaging data collection. B) Summary figure of the daily prenatal drug exposure procedure. C) Example fetus, G13.5, imaged using VEVO2100, with example waveform analysis Fig. D) Average blood alcohol concentrations among alcohol-exposed subjects. E) Rates of loss of righting reflex (LORR) in drug-exposed dams immediately following drug exposure. F) Gestational weight gain across drug-exposed dams. Abbreviations G = Gestational Day, BAC = Blood Alcohol Concentration, MCA = Middle Cerebral Artery, ICA = Internal Carotid Artery, LORR = Loss of Righting Reflex, CON = Control, ALC = Alcohol, CB = Cannabinoid, ALC + CB = Alcohol + Cannabinoid. Symbols: * indicates p < 0.05, *** indicates p < 0.001

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BMC Pregnancy and Childbirth

ISSN: 1471-2393

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