Table 2 Summary statistics using the fixed-effects model in assessing the effect of aspirin on pregnancy outcomes in nulliparous women
Outcomes | Trials, n | Participants, n | Fixed effect, relative risk (95% CI) | P value | I2, % |
|---|---|---|---|---|---|
Preterm birth less than 37 weeks of gestation | 6 | 26,086 | 0.96 (0.90, 1.02) | 0.18 | 31 |
Preterm birth less than 34weeks of gestation | 3 | 14,647 | 0.84 (0.71, 0.99) | 0.04 | 0 |
Postpartum hemorrhage | 4 | 24,143 | 1.32 (1.14, 1.54) | 0.0003 | 0 |
Placental abruption | 3 | 6354 | 2.18 (1.10, 4.32) | 0.02 | 16 |
Cesarean section | 6 | 24,588 | 1.05 (1.00, 1.11) | 0.05 | 0 |
Any hypertensive disorder of pregnancy | 7 | 26,168 | 1.05 (0.96, 1.14) | 0.28 | 9 |
Small for gestational age | 5 | 18,005 | 0.96 (0.91, 1.02) | 0.16 | 0 |