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Table 2 Urinary concentrations of unadjusted (ng/mL) and adjusted PAEs (µg/g Cr)

From: Association of maternal phthalates exposure and metabolic gene polymorphisms with congenital heart diseases: a multicenter case-control study

Diether phthalate

Phthalate metabolites

(µg/g creatinine)

LOD

(ng/mL)

Concentration≥

LOD, n (%)

Median (IQR)

P-Valuea

Total participants

(n = 529)

Controls

(n = 268)

CHDs Cases

(n = 245)

DiBP

MiBP

0.50

511(99.61%)

10.23(5.94,17.43)

10.43(6.09,18.77)

10.01(5.53,16.12)

0.452

DnBP

MnBP

0.50

513(100%)

36.9(17.58,71.91)

34.08(16.6,68.19)

41.11(19.02,76.23)

0.106

BBzP

MBzP

0.05

434(84.60%)

0.08(0.04,0.23)

0.09(0.04,0.19)

0.08(0.04,0.28)

0.407

DEHP

MEHP

0.50

492(95.90%)

2.53(1.30,4.58)

2.71(1.41,4.95)

2.37(1.19,4.04)

0.052

 

MEHHP

0.05

513(100%)

2.45(1.39,4.11)

2.35(1.38,3.85)

2.51(1.41,4.84)

0.137

 

MEOHP

0.05

513(100%)

1.44(0.86,2.45)

1.40(0.83,2.3)

1.48(0.88,2.81)

0.176

 

MECPP

0.10

513(100%)

5.48(3.29,9.10)

5.43(3.25,8.25)

5.49(3.38,10.36)

0.219

 

MCMHP

0.20

513(100%)

1.59(1.12,2.58)

1.60(1.16,2.31)

1.55(1.10,2.89)

0.489

  1. aP values for the Mann‒Whitney U test between case and control group