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Table 2 Univariable analysis of factors associated with adverse birth outcomes among women enrolled in the study (N = 1916)

From: Risk factors of adverse birth outcomes among a cohort of pregnant women in Coastal Kenya, 2017–2019

Variable

Total

n (%)

Had adverse birth outcome

n (%)

No adverse birth outcome

n (%)

RR (95% CI)

p- value

Age N = 1905

Median (IQR)

 

28.5(24–33)

28.0(24–33)

1.0(0.9-1.0)

0.567

15–19

62(3.3)

17(4.5)

45(2.9)

1.4 (0.9–2.2)

0.138*

20–35

1592 (83.6)

291(77.4)

1244(81.4)

Ref

 

36–46

251 (13.1)

68(18.1)

240 (15.7)

1.2(0.9–1.5)

 

Facility type N = 1916

Private

654 (34.1)

126(33.2)

528(34.3)

1.0(0.8–1.3)

0.684

Public

1262 (65.9)

253(66.7)

1009(65.6)

Ref

 

Education N = 1885

    

0.107*

Primary

490 (26.0)

112(29.8)

378(25.0)

1.1(0.9–1.4)

 

Secondary

857 (45.5)

155(41.3)

702(46.5)

0.9(0.7–1.1)

 

College

538 (28.5)

108(28.8)

430(28.4)

Ref

 

Employment N = 1915

     

Employed

754 (39.4)

144(37.9)

610(39.7)

Ref

0.631

Self employed

285 (14.9)

62(16.4)

223(14.5)

1.1(0.9–1.4)

 

Unemployed

876 (45.7)

173(45.7)

703(4.8)

1.0(0.8–1.5)

 

Marital status N = 1916

Married

1699 (88.7)

332(87.6)

1367(88.9)

1.0(0.7–1.4)

0.461

Single

217 (11.3)

47(12.4)

170(11.1)

Ref

 

History of chronic illness N = 1905

Yes

116 (6.1)

30 (8.0)

86 (5.6)

1.3(0.9–1.8)

0.084*

No

1789 (93.9)

345(92.0)

1444 (94.4)

Ref

 

Substance use N = 1916

Yes

75 (3.9)

18(4.7)

57(3.7)

1.2(0.8–1.9)

0.349

No

1841 (96.1)

361 (95.2)

1480 (96.3)

Ref

 

Anaemia at enrolment N = 1916

Yes

492 (25.7)

93(24.5)

399(25.9)

0.9(0.8–1.2)

0.572

No

1424 (74.3)

286(75.5)

1138 (74.0)

Ref

 

Folic acid intake N = 1916

Yes

494 (25.7)

57(22.9)

437(26.2)

0.8(0.6–1.1)

0.280

No

1422 (74.2)

191 (77.0)

1231 (73.8)

Ref

 

Short stature N = 1897

Yes

32(1.7)

7(1.9)

25(1.6)

1.1(0.6–2.1)

0.769

No

1865 (98.3)

369(98.1)

1496(98.4)

Ref

 

Syphilis status N = 1728

    

0.371

Positive

26(1.5)

7(2.0)

19(1.4)

1.3(0.7–2.5)

 

Negative

1702(98.5)

338(97.9)

1364(98.6)

  

MUAC of the pregnant women = 1479

Median (IQR)

28(26–31)

28(25.4–30.5)

28(26–31)

0.9(0.9-1.0)

0.942

Underweight

107(7.3)

26(9.0)

81(6.8)

1.2(0.8–1.7)

0.259

Normal

826(55.9)

165(57.3)

661(55.5)

Ref

 

Overweight

546(36.9)

97(33.7)

449(37.7)

0.8(0.7–1.1)

 

HIV status N = 1791

Positive

308(17.2)

77(21.6)

231(16.1)

1.3 (1.0-1.7)

0.013*

Negative

1483 (82.8)

279 (78.4)

1204 (83.9)

Ref

 

On HAART N = 303

Yes

278 (90.3)

69(80.8)

209(92.1)

0.9(0.5–1.7)

0.725

No

25 (8.1)

7(9.2)

18(7.9)

Ref

 

Mode of delivery

Caesarean section

403 (26.3)

74 (23.9)

329 (27.0)

1.1 (0.9–1.4)

0.273

Vaginal delivery

1127 (73.7)

236 (76.1)

891 (73.0)

Ref

 

Number of previous pregnancies (Parity) N = 1916

0

549 (28.7)

120(31.7)

429(27.9)

1.2(0.9–1.4)

0.197*

1–3

1284 (67.0)

239(63.0)

1045(68.0)

1

 

> 3

83 (4.3)

20(5.3)

63 (4.1)

1.2(0.9–1.9)

 

History of poor birth outcome among multiparous women N = 1367

Yes

508(37.1)

124(47.9)

384(34.7)

1.6(1.2–1.9)

< 0.001*

No

859 (62.8)

135 (52.1)

724 (65.3)

Ref

 

Gestation age at first ANC visit N = 1916

Median gestation age at first ANC visit (IQR)

 

17.7 (13.6–21.7)

17.8 (13.6–22.7)

0.9 (0.9-1.0)

0.699

High blood pressure at enrolment N = 1913

Yes

22 (1.2)

10(2.6)

12(0.8)

2.3(1.4–3.7)

0.002*

No

1891 (98.9)

369 (97.4)

1522 (99.2)

Ref

 

Fever in current pregnancy N = 1915

Yes

88 (4.6)

25(6.6)

63(4.1)

1.7(1.1–2.6)

0.038*

No

1827 (95.4)

354(93.4)

1473 (95.9)

Ref

 

Consistent use of mosquito net N = 1916

Yes

1457(76.0)

291(76.9)

1166(75.9)

1.0(0.8–1.3)

0.707

No

459 (23.9)

88 (23.2)

371 (24.1)

Ref

 
  1. Abbreviations: antenatal care (ANC), human immunodeficiency virus (HIV), interquartile range (IQR), risk ratio (RR), adjusted risk ratio (aRR), confidence interval (CI), highly active antiretroviral therapy (HAART), mid upper arm circumference (MUAC), reference category(ref)
  2. *Variables eligible for inclusion in the multivariable model (p ≤ 0.25)