From: Association of maternal serum uric acid levels with LBW/SGA: a large retrospective cohort study
UA, μmol/L | Total (n=69,674) | SGA (n (%)) | Crude model | Adjusted model | ||
---|---|---|---|---|---|---|
OR (95% CI) | P-value | OR (95% CI) | P-value | |||
Total | ||||||
Q1(<213.8) | 17,391 | 1352(7.8) | ref | ref | ||
Q2(213.8-242.0) | 17,362 | 1466(8.4) | 1.09(1.01,1.18) | 0.022 | 1.09(1.01,1.18) | 0.03 |
Q3(242.0-273.5) | 17,567 | 1572(9.0) | 1.17(1.09,1.27) | <0.001 | 1.18(1.09,1.28) | <0.001 |
Q4(≥273.5) | 17,454 | 1893(10.8) | 1.44(1.34,1.55) | <0.001 | 1.43(1.32,1.54) | <0.001 |
P for trend | <0.001 | <0.001 | ||||
First trimester | ||||||
Q1(<180.0) | 14,588 | 1270(8.7) | ref | ref | ||
Q2(180.0-205.0) | 14,435 | 1338(9.3) | 1.07(0.99,1.16) | 0.093 | 1.07(0.98,1.16) | 0.12 |
Q3(205.0-234.0) | 14,868 | 1328(8.9) | 1.03(0.95,1.11) | 0.494 | 1.03(0.94,1.11) | 0.551 |
Q4(≥234.0) | 14,733 | 1282(8.7) | 1.00(0.92,1.08) | 0.99 | 1.01(0.93,1.10) | 0.816 |
P for trend | 0.740 | 0.950 | ||||
Second trimester | ||||||
Q1(<194.0) | 10,823 | 951(8.8) | ref | ref | ||
Q2(194.0-222.0) | 11,033 | 993(9.0) | 1.03(0.94,1.13) | 0.579 | 1.03(0.94,1.13) | 0.542 |
Q3(222.0-253.0) | 11,105 | 1072(9.7) | 1.11(1.01,1.22) | 0.027 | 1.14(1.04,1.25) | 0.006 |
Q4(≥253.0) | 11,084 | 1052(9.5) | 1.09(0.99,1.19) | 0.071 | 1.13(1.03,1.24) | 0.013 |
P for trend | 0.025 | 0.002 | ||||
Third trimester | ||||||
Q1(<227.5) | 17,064 | 1327(7.8) | ref | ref | ||
Q2(227.5-261.3) | 17,055 | 1401(8.2) | 1.06(0.98,1.15) | 0.136 | 1.08(0.99,1.17) | 0.078 |
Q3(261.3-299.0) | 17,081 | 1466(8.6) | 1.11(1.03,1.20) | 0.007 | 1.13(1.04,1.23) | 0.002 |
Q4(≥299.0) | 17,069 | 1943(11.4) | 1.52(1.42,1.64) | <0.001 | 1.49(1.38,1.61) | <0.001 |
P for trend | <0.001 | <0.001 |