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Table 1 Variables where harmonization was possible, across cohorts

From: A harmonized analysis of five Canadian pregnancy cohort studies: exploring the characteristics and pregnancy outcomes associated with prenatal alcohol exposure

Harmonized Variable

AOFa

APrONb

FAMILYc

OBSd

3De

Maternal behaviors and risk factors

 Alcohol use

  Alcohol consumption before pregnancy (yes/no)

-f

Xg

-

X

-

  Alcohol consumption during year prior to pregnancy (yes/no)

X

-

X

X

X

  Alcohol consumption during pregnancy (yes/no)

X

X

X

X

X

  Binge drinking during year prior to pregnancy (yes/no)h

X

-

-

X

X

  Binge drinking during pregnancy (yes/no)

X

-

X

X

X

 Age

  Age at first questionnaire response during current pregnancy (integer)

X

-

X

X

X

  Age at delivery for current pregnancy/birth (integer)

X

X

X

-

X

 Ethnicity

  Ethnic background – White (yes/no)

X

X

X

X

X

 Marital status

  Marital status (categorical)

X

X

-

X

X

 Education

  Highest level of education completed (categorical)

X

X

-

X

X

 Employment

  Employment status (yes/no)

X

-

X

X

X

 Income

  Income level (categorical)

X

X

X

X

X

 Smoking

  Cigarette smoking before pregnancy (yes/no)

-

X

X

X

X

  Cigarette smoking during pregnancy (yes/no)

X

X

X

X

X

 Physical Measures

  BMI before pregnancy (continuous)

X

X

X

X

X

Current Pregnancy

 Maternal reproductive history

  Gravidity (integer)

X

X

X

X

X

  Previous live births (integer)

X

X

X

X

X

 Maternal co-morbidities

  Gestational hypertension (yes/no)

X

X

X

X

X

  Gestational diabetes (yes/no)

X

X

X

X

X

  Pre-eclampsia or eclampsia (yes/no)

X

X

X

X

-

 Birth outcomesi

  Live birth (yes/no)

X

X

X

X

X

  Gestational age at delivery (integer)

X

X

X

X

X

  Birth weight (yes/no)

X

X

X

X

X

  1. aAll Our Families
  2. bAlberta Pregnancy Outcomes and Nutrition
  3. cFamily Atherosclerosis Monitoring In earLY life
  4. dOntario Birth Study
  5. e3D Study—Design, Develop, Discover
  6. f-Variable not possible to harmonize
  7. g X Variable was harmonized
  8. h Binge drinking was defined as consuming 5 or more drinks on one occasion in AOF, APrON, FAMILY, and 3D, and as consuming 4 or more drinks on o ne occasion in OBS
  9. i Birth outcomes focus on singleton births or the first of a multiple birth