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Table 2 Performance of the classifiers

From: Performance of whole-genome promoter nucleosome profiling of maternal plasma cell-free DNA for prenatal noninvasive prediction of fetal macrosomia: a retrospective nested case-control study in mainland China

Classifiers

LR

SVM

 

Cohort

AUC (95% CI)

Acc

Sen

Spe

AUC (95% CI)

Acc

Sen

Spe

P-value

Training

0.7793 (0.7094–0.8491)

81.28%

72.34%

83.51%

0.8298 (0.7675–0.8921)

84.26%

80.85%

85.11%

0.111

Internal

0.8393 (0.7608–0.9178)

80.00%

90.48%

77.38%

0.8512 (0.7853–0.9171)

79.05%

95.24%

75.00%

0.655

External-1

0.8023 (0.7361–0.8686)

79.53%

81.40%

79.07%

0.8459 (0.7822–0.9097)

86.51%

81.40%

87.79%

0.219

External-2

0.7108 (0.6404–0.7811)

71.37%

70.59%

71.57%

0.7941 (0.7309–0.8573)

80.00%

78.43%

80.39%

0.005

All

0.7716 (0.7352–0.808)

77.53%

76.54%

77.78

0.8256 (0.7927–0.8586)

82.84%

82.10%

83.02%

< 0.001

  1. AUC Area under the receiver operating characteristic curve, 95% CI 95% confidence interval