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Table 4 Rates respiratory distress syndrome (RDS) at early (<32 weeks) and late (≥39 weeks) gestation per 1000 live births and unadjusted odds ratios and 95 % confidence intervals (CI) expressing the association between neonatal co-morbidity and RDS, United States, 2005–2006

From: Heterogeneity of respiratory distress syndrome: risk factors and morbidity associated with early and late gestation disease

 

RDS <32 weeks

RDS ≥39 weeks

No.

Rate per 1000

Odds ratio [95 % CI]

No.

Rate per 1000

Odds ratio [95 % CI]

Apgar at 5 min

<4

404

111.5

1.03 [0.92, 1.14]

108

45

33.1 [27.2, 40.2]

4–6

1272

142.1

1.36 [1.27, 1.45]

421

34.1

24.8 [22.4, 27.5]

≥7

5688

108.8

Reference

3741

1.4

Reference

Small for gestational age

786

113

1.00 [0.92, 1.08]

562

2.6

1.73 [1.58, 1.89]

Neonatal seizures

30

428.6

5.90 [3.67, 9.47]

30

22.6

14.4 [10.0, 20.7]

Ventilation ≥ 30 min

4416

320.9

7.64 [7.26, 8.04]

695

93.6

75.9 [69.7, 82.6]

Ventilation <30 min

503

145.4

1.36 [1.23, 1.50]

351

9.5

6.36 [5.70, 7.10]

Birth asphyxia

4983

255.5

6.20 [5.88, 6.53]

1106

23.5

19.7 [18.4, 21.2]

Meconium aspiration syndrome

10

192.3

1.87 [0.94, 3.72]

228

57.6

39.8 [34.7, 45.6]

All live births

7450

113.2

-

4287

1.6

-

  1. Birth asphyxia was defined as Apgar at 5 min <4, presence of neonatal seizures, or any assisted ventilation. Births with missing Apgar values excluded from the analysis