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Table 4 Factors associated with MTCT of HIV

From: High prevalence of herpes simplex virus (HSV)- type 2 co-infection among HIV-positive women in Ukraine, but no increased HIV mother-to-child transmission risk

 

Number with MTCT (%)

Odds ratio (95 % CI)

Adjusted odds ratio (95 % CI), p value n = 1286a

Length of gestation

 ≥37 completed weeks

33/1204 (2.7)

1

1

 <37 completed weeks

4/109 (3.7)

0.73 (0.25–2.09) p = 0.553

0.93 (0.30–2.82) p = 0.891

Mode of delivery

 Vaginal

27/942 (2.9)

1

1

 Elective CS

9/305 (3.0)

1.03 (0.48–2.21) p = 0.945

0.76 (0.32–1.80) p = 0.529

 Emergency CS

1/58 (1.7)

0.58 (0.08–4.38) p = 0.602

1.04 (0.13–8.28) p = 0.973

Antenatal/intrapartum ARVs

   

 cART

11/607 (1.8)

1

1

 ZDV +/− sdNVP

20/666 (3.0)

0.61 (0.29–1.28) p = 0.190

0.59 (0.27–1.31) p = 0.194

 None or sdNVP only

6/42 (14.3)

5.31 (2.01–14.03) p <0.01

3.42 (1.19–9.85) p = 0.023

IDU history

 No

30/1057 (2.8)

1

1

 Yes

7/254 (2.8)

0.98 (0.43–2.26) p = 0.964

1.18 (0.46–2.99) p = 0.735

HSV-2 serostatus

   

 Negative

13/404 (3.2)

1

1

 Positive

24/916 (2.6)

0.80 (0.41–1.60) p = 0.553

1.43 (0.54–3.77) p = 0.474

  1. a Adjusted additionally for time period of delivery (2007–09 vs. 2010–12) and including random effect term for centre of enrolment