Group of birth defect (ICD-10 codes) | 1973-2000 | 2001-2011 | p-value1 | ||
---|---|---|---|---|---|
Number (N) of newborns: 23 822 | Number (N) of newborns: 6626 | ||||
N of BD | Prevalence2 | N of BD | Prevalence2 | ||
Congenital malformations of the nervous system (Q00-Q07) | 40 | 1.7 (1.2-2.2) | 14 | 2.1 (1.0-3.2) | 0.450 |
Congenital malformations of eye, ear, face and neck (Q10-Q18) | 11 | 0.5 (0.2-0.7) | 6 | 0.9 (0.2-1.6) | 0.174 |
Congenital malformations of the circulatory system (Q20-Q28) | 58 | 2.4 (1.8-3.1) | 7 | 1.1 (0.3-1.8) | 0.032 |
Congenital malformations of the respiratory system(Q30-Q34) | 26 | 1.1 (0.7-1.5) | 3 | 0.5 (0–1.0) | 0.138 |
Cleft lip and cleft palate (Q35-Q37) | 31 | 1.3 (0.8-1.8) | 7 | 1.1 (0.3-1.8) | 0.624 |
Congenital malformations of the digestive system (Q38-Q45) | 29 | 1.2 (0.8-1.7) | 7 | 1.1 (0.3-1.8) | 0.743 |
Congenital malformations of genital organs (Q50-Q56) | 86 | 3.6 (2.8-4.4) | 26 | 3.9 (2.4-5.4) | 0.696 |
Congenital malformations of the urinary system (Q60-Q64) | 21 | 0.9 (0.5-1.3) | 113 | 17.1 (14.0-20.2) | <0.0001 |
Congenital malformations and deformations of the musculoskeletal system (Q65-Q79) | 323 | 13.5 (12.1-15.0) | 63 | 9.5 (7.2-11.9) | 0.010 |
Other congenital malformations, excluding multiple (Q80-Q89, excluding Q 89.7) | 98 | 4.1 (3.3-4.9) | 12 | 1.8 (0.8-2.8) | 0.007 |
Chromosomal abnormalities (Q90-Q99) | 17 | 0.7 (0.4-1.1) | 5 | 0.8 (0.1-1.4) | 0.807 |
Multiple congenital malformation, not classified | 76 | 3.2 (2.5-3.9) | 20 | 3.0 (1.7-4.4) | 0.937 |