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Table 1 Adverse events following influenza immunisation reported by pregnant and non-pregnant women – FASTMum, Western Australia, Australia, 19 March-15 May 2014

From: A prospective cohort study comparing the reactogenicity of trivalent influenza vaccine in pregnant and non-pregnant women

 

Pregnant (n = 947)

Non-pregnant (n = 275)

Fisher’s exact test p-value

AOR p-value

 

n

Percent (95% CI)

n

Percent (95% CI)

Any reaction**

141

13.0 (11.0-15.0)

51

17.5 (13.1-21.8)

.19

.33

Systemic reaction

85

9.0 (7.1-10.8)

28

10.2 (6.6-13.8)

.55

.36

Fever

15

1.6 (0.8-2.4)

16

5.8 (3.0-8.6)

<.01*

<.01*

Headache

27

2.9 (1.8-3.9)

13

4.7 (2.2-7.3)

<.01*

.04*

Fatigue

40

4.2 (2.9-5.5)

13

4.7 (2.2-7.3)

.74

.68

Vomiting

7

0.7 (0.2-1.3)

0

(0.0-0.7)

.36

.95

Rigors

5

0.5 (0.1-1.0)

2

0.7 (0.0-1.7)

.66

.89

Cold/flu-like

37

3.9 (2.7-5.1)

10

3.6 (1.4-5.9)

.50

.69

Myalgia

11

1.2 (0.5-1.8)

5

1.8 (0.2-3.4)

.37

.71

Nausea

8

0.8 (0.3-1.4)

1

0.4 (0.0-1.1)

.69

.59

Malaise

4

0.4 (0.0-0.8)

1

0.4 (0.0-1.1)

.69

.51

Local reaction

45

4.8 (3.4-6.1)

20

7.3 (4.2-10.4)

.13

.13

Other reaction

6

0.6 (0.1-1.1)

2

0.7 (0.0-1.7)

.57

.89

  1. **Any reaction was defined as replying “yes” to the question “did you experience any fever, illness, or reaction following your vaccination?”.
  2. *Significant at α = .05.
  3. AOR, adjusted odds ratio – adjusted for age and residence (metropolitan/non-metropolitan).
  4. CI, confidence interval.