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Table 2 Multivariate Regression Coefficients for the Association of Maternal Risk Factors with Placental Weight, Thickness and Chorionic Plate Area by Placental Growth

From: Maternal risk factors for abnormal placental growth: The national collaborative perinatal project

 

Placental Growth

 

Placental Restriction

(< 10th percentile)

Placental Hypertrophy

(> 90th percentile)

 

Weight

(g)

Thickness

(mm)

Chorionic

Plate Area

(cm2)

Weight

(g)

Thickness

(mm)

Chorionic

Plate Area

(cm2)

Maternal age (per 5 years)

1.00 (0.99, 1.01)

1.02* (1.01, 1.03)

0.99* (0.98, 0.99)

1.01 (1.00, 1.02)

0.99 (0.98, 1.00)

1.04* (1.03, 1.05)

AnnualFamily Income

      

< $5,000 vs ≥ $5,000

0.88 (0.80, 0.98)

0.79* (0.71, 0.89)

0.87 (0.79, 0.96)

1.19* (1.08, 1.32)

0.92 (0.83, 1.02)

1.21* (1.07, 1.34)

Maternal Education

      

< 12 yrs vs ≥ 12 yrs

0.83* (0.76, 0.91)

0.78* (0.71, 0.86)

0.87* (0.80, 0.95)

1.09 (0.99, 1.19)

1.15 (1.04, 1.26)

0.94 (0.85, 1.04)

Maternal Race

      

Black vs White

1.66* (1.51, 1.82)

3.22* (2.90, 3.58)

1.36* (1.24, 1.49)

0.57* (0.51, 0.63)

0.70* (0.64, 0.77)

0.80* (0.72, 0.89)

Smoking Status

      

Light vs Non-smoker

0.92 (0.84, 1.02)

1.03 (0.93, 1.13)

0.94 (0.86, 1.03)

0.95 (0.85, 1.05)

0.89 (0.81, 0.99)

1.09 (0.98, 1.21)

Heavy vs Non-smoker

1.00 (0.89, 1.13)

1.11 (0.98, 1.27)

0.92 (0.82, 1.03)

0.96 (0.85, 1.09)

0.85 (0.75, 0.97)

1.12 (0.98, 1.27)

Parity

      

Parous vs Nulliparous

0.89 (0.80, 0.98)

0.98 (0.88, 1.10)

1.06 (0.96, 1.17)

1.25* (1.11, 1.40)

1.32* (1.18, 1.48)

1.09 (0.96, 1.23)

Anemia

      

Yes vs No

0.67* (0.60, 0.74)

1.00 (0.91, 1.56)

0.80* (0.72, 0.89)

1.50* (1.34, 1.67)

1.18 (1.05, 1.32)

1.45* (1.30, 1.63)

Gestational Diabetes

      

Yes vs No

0.77 (0.51, 1.16)

0.77 (0.51, 1.18)

0.68 (0.45, 1.02)

1.75* (1.33, 2.32)

1.29 (0.94, 1.76)

1.59* (1.18, 2.13)

Hypertensive Disease

      

Yes vs No

1.98* (1.54, 2.55)

1.19 (0.91, 1.56)

1.86* (1.46, 2.37)

0.62* (0.46, 0.84)

0.69 (0.50, 0.95)

0.89 (0.66, 1.19)

Pre-pregnancy BMI (per 1 kg/m2)

0.91* (0.90, 0.92)

0.98* (0.97, 0.99)

0.93* (0.92, 0.95)

1.10* (1.06, 1.08)

1.05* (1.04, 1.06)

1.04* (1.03, 1.05)

Pregnancy Weight Gain (per 1 kg)

0.93* (0.92, 0.94)

0.99 (0.98, 1.00)

0.96* (0.95, 0.97)

1.07* (1.06, 1.08)

1.03* (1.02, 1.04)

1.05* (1.04, 1.06)

  1. *P < 0.0045 (Bonferroni-adjusted p-value applied for significance testing)
  2. All results presented as Regression co-efficient (95% Confidence Interval)
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BMC Pregnancy and Childbirth

ISSN: 1471-2393

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