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Table 3 Percentage inhibition (%) of MLR-Bf significant IgG and its isotypes

From: Characterization of mixed lymphocyte reaction blocking antibodies (MLR-Bf) in human pregnancy

Different group of subjects

Proportionate change in percentage inhibition of MLR-Bf significant IgG and its isotypes in terms of interquartile range (IQR)

 

IgG

IgG1

IgG2

IgG3

IgG4

 

W × H (1:2)

H × W (2:1)

W × H (1:2)

H × W (2:1)

W × H (1:2)

H × W (2:1)

W × H (1:2)

H × W (2:1)

W × H (1:2)

H × W (2:1)

Ist trimester

39 (35–67)

26 (21–63)

22 (18–28)

24 (15–26)

17 (-11–37)

21 (7–42)

68 (61–68) *

64 (60–63) *

19 (17–45)

17 (11–21)

IInd trimester

42 (28–71)

39 (35–64)

18 (15–24)

17 (14–19)

12 (3–33)

11 (9–15)

61 (63–70) *

62(61–67) *

29 (-14–33)

4 (-17–8)

IIIrd trimester

27 (21–62)

35 (27–67)

-14 (-27–9)

13 (-8–27)

15 (9–23)

17 (14–21)

67 (61–82) *

71(62–76) *

15 (15–28)

13 (9–16)

Post delivery period

44 (20–68)

25 (23–68)

17 (-3–20)

15 (10–30)

5 (-9–19)

11 (7–31)

47 (14–47)

41(23–52)

8 (4–17)

11 (6–22)

Pre immunized RSA Women

34 (28–47)

28 (23–61)

6 (-12–9)

-6 (-11–2)

2 (24–11)

5 (-22–7)

43 (17–37)

38(21–36)

6 (-12–6)

8 (5–19)

Post immunized RSA Women

51 (44–69)

60 (57–73)

-7 (-16–7)

4 (-12–6)

12 (6–31)

21 (11–29)

67 (64–82) *

67(62–71) *

21 (19–26)

15 (10–30)

Healthy male

-9 (-21–2)

-17 (-8–4)

-17 (-19–2)

-8 (-11–3)

-15 (-27–5)

4 (-17–2)

-11 (-19–9)

-12(-18–7)

-6 (-29–4)

-11 (-18–19)

Unmarried females

-17 (-24–6)

-23 (-35–2)

-7 (-11–3)

3 (-7–10)

-5 (-17–4)

9 (-21–12)

15 (-11–3)

12(-6–17)

14 (11–22)

25 (24–27)

  1. 1:2 (non irradiated cells of control female × irradiated cells of control male), 2:1 (non irradiated cells of control male × irradiated cells of control female) W = wife, H = husband. Values given in the table are calculated as percentage inhibition (%) against the base line measurement and shown as median and interquartile range(IQR), n = 10.*P < 0.001