From: Characterization of mixed lymphocyte reaction blocking antibodies (MLR-Bf) in human pregnancy
Different group of subjects | Proportionate change in percentage inhibition of MLR-Bf significant IgG and its isotypes in terms of interquartile range (IQR) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
 | IgG | IgG1 | IgG2 | IgG3 | IgG4 | |||||
 | W × H (1:2) | H × W (2:1) | W × H (1:2) | H × W (2:1) | W × H (1:2) | H × W (2:1) | W × H (1:2) | H × W (2:1) | W × H (1:2) | H × W (2:1) |
Ist trimester | 39 (35–67) | 26 (21–63) | 22 (18–28) | 24 (15–26) | 17 (-11–37) | 21 (7–42) | 68 (61–68) * | 64 (60–63) * | 19 (17–45) | 17 (11–21) |
IInd trimester | 42 (28–71) | 39 (35–64) | 18 (15–24) | 17 (14–19) | 12 (3–33) | 11 (9–15) | 61 (63–70) * | 62(61–67) * | 29 (-14–33) | 4 (-17–8) |
IIIrd trimester | 27 (21–62) | 35 (27–67) | -14 (-27–9) | 13 (-8–27) | 15 (9–23) | 17 (14–21) | 67 (61–82) * | 71(62–76) * | 15 (15–28) | 13 (9–16) |
Post delivery period | 44 (20–68) | 25 (23–68) | 17 (-3–20) | 15 (10–30) | 5 (-9–19) | 11 (7–31) | 47 (14–47) | 41(23–52) | 8 (4–17) | 11 (6–22) |
Pre immunized RSA Women | 34 (28–47) | 28 (23–61) | 6 (-12–9) | -6 (-11–2) | 2 (24–11) | 5 (-22–7) | 43 (17–37) | 38(21–36) | 6 (-12–6) | 8 (5–19) |
Post immunized RSA Women | 51 (44–69) | 60 (57–73) | -7 (-16–7) | 4 (-12–6) | 12 (6–31) | 21 (11–29) | 67 (64–82) * | 67(62–71) * | 21 (19–26) | 15 (10–30) |
Healthy male | -9 (-21–2) | -17 (-8–4) | -17 (-19–2) | -8 (-11–3) | -15 (-27–5) | 4 (-17–2) | -11 (-19–9) | -12(-18–7) | -6 (-29–4) | -11 (-18–19) |
Unmarried females | -17 (-24–6) | -23 (-35–2) | -7 (-11–3) | 3 (-7–10) | -5 (-17–4) | 9 (-21–12) | 15 (-11–3) | 12(-6–17) | 14 (11–22) | 25 (24–27) |