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Table 1 Population characteristics of HIV-infected women spontaneously delivering singleton, HIV-uninfected infants

From: Correlates and outcomes of preterm birth, low birth weight, and small for gestational age in HIV-exposed uninfected infants

 

N

Median (IQR) or proportion (n)

Sociodemographic

  

  Married

413

90% (372)

  Employed

413

30% (123)

  Years education

408

8 (8–11)

Physical and Obstetric (Current pregnancy)

  

  Age (years)

413

25 (22–28)

  Body mass index at 32 weeks

400

24 (23–26)

  Parity

409

1 (1–2)

  Pre-eclampsia

408

1.5% (6)

  Eclampsia

407

0.25% (1)

  Place of delivery

  

    Kenyatta National Hospital

412

85% (350)

    Other facility

412

6.1% (25)

    Home

412

7.5% (31)

    En route to hospital

412

1.5% (6)

  Caesarean section

394

15% (58)

  Alcohol use

410

3.9% (16)

  Cigarette smoking

412

1.2% (5)

Vaginal infections at 32 weeks

  

  Bacterial vaginosis

385

37% (144)

  Candida

408

30% (124)

  Cervical PMN ≥3 per high-powered field

336

61% (204)

  Abnormal vaginal discharge

408

50% (204)

  Cervical blood

408

4.7% (19)

  Trichomonas vaginalis

408

16% (65)

  Chlamydia trachomatis

407

3.9% (16)

  Treponema pallidum

409

2.4% (10)

  Neisseria gonorrhoeae

407

2.0% (8)

  Any sexually transmitted infectiona

413

21% (88)

Immunologic and virologic

  

  CD4 cells/mm3 <350

401

34% (137)

  CD4 percent <15

401

15% (60)

  Log10 plasma HIV-1 RNA load

396

4.7 (4.2-5.2)

  Log10 cervical HIV-1 RNA load

315

2.0 (1.4-2.9)

  Cervical HIV DNA detectable

315

72% (227)

Delivery

  

  Baby female

412

46% (191)

  Dubowitz estimated maturity (weeks)

335

40 (39–41)

  Premature

335

9.9% (33)

   Dubowitz estimated maturity in preterm (weeks)

33

35 (34–36)

  Low birth weight

332

6.0% (20)

   Birth weight in low birth weight infants (kg)

332

2.2 (1.5-2.4)

  Small for gestational age

311

9.0% (28)

  1. Notes. All clinical assessments and laboratory measurements were performed at 32 weeks gestation. aIncludes laboratory-confirmed Neisseria gonorrhoeae, Trichomonas vaginalis, Chlamydia trachomatis, and Treponema pallidum.