Trisomy 18 (N = 17) | Trisomy 13 (N = 6) | |
---|---|---|
Cardiac | ||
Ventricular septal defect | 11 | 1 |
Transposition of Great Arteries | 1 | 0 |
Patent ductus arteriosus | 0 | 1 |
Cerebral | ||
Holoprosencephaly | 0 | 2 |
Cerebral ventriculomegaly | 2 | 0 |
Microcephaly | 1 | 1 |
Dandy Walker variant | 1 | 1 |
Structural | ||
Cleft lip/palate | 2 | 4 |
Talipes/rockerbottom feet | 5 | 2 |
Clenched hands | 5 | 1 |
Polydactyly | 0 | 1 |
Low set ears | 1 | 0 |
Short long bones | 3 | 0 |
Overlapping fingers | 0 | 1 |
Micrognathia | 2 | 0 |
Ocular hypotelorism | 1 | 1 |
Syndactyly | 2 | 0 |
Gastrointestinal | ||
Small/absent stomach | 3 | 1 |
Omphalocele | 4 | 0 |
Umbilical herniation | 1 | 0 |
Respiratory | ||
Pleural effusion | 1 | 0 |
Diaphragmatic hernia | 3 | 0 |
Renal | ||
Enlarged/cystic kidneys | 1 | 3 |