Table 2 Crude and adjusted association between EONI, clinical and histological chorioamnionitis and gestational age at delivery, antibiotics at admission, management of delivery, and routinely used infectious markers.
Early Onset Neonatal Infection | Clinical Chorioamnionitis | Histological Chorioamnionitis | ||||
|---|---|---|---|---|---|---|
Binary Variables | OR [95% CI] | Adjusted OR [95% CI]a | OR [95% CI] | Adjusted OR [95% CI]a | OR [95% CI] | Adjusted OR [95% CI]a |
Gestational Age | ||||||
< 37 | 0.8 [0.2, 3.6] | - | 0.3 [0.0, 2.2] | - | 1.1 [0.4, 3.1] | - |
≥ 37 | 1 | 1 | 1 | |||
Antibiotic at admission | ||||||
Yes | 0.7 [0.3, 2.1] | - | 0.5 [0.2, 1.5] | - | 0.6 [0.2, 1.3] | - |
No | 1 | 1 | 1 | |||
Management of delivery | ||||||
Expectant | 0.4 [0.1, 1.6] | - | 0.6 [0.2, 1.8] | - | 1.6 [0.8, 3.5] | - |
Active | 1 | 1 | 1 | |||
Abnormal bacterial colonisation, genital tract | ||||||
Yes | 2.7 [1.0, 7.2] | 2.2 [0.7, 6.6] | 1.8 [0.7, 4.6] | - | 1.2 [0.5, 2.7] | - |
No | 1 | 1 | 1 | 1 | ||
Continuous variables b | Coefficient [95% CI] | Adjusted Coefficient [95% CI] a | Coefficient [95% CI] | Adjusted Coefficient [95% CI] a | Coefficient [95% CI] | Adjusted Coefficient [95% CI] a |
CRP(mg/l) | 0.064 [0.035, 0.093] | 0.055 [0.024, 0.086] | 0.039 [0.016, 0.062] | 0.039 [0.016, 0.062] | 0.051 [0.022, 0.080] | 0.051 [0.022, 0.080] |
WBC (giga/l) | 0.015 [0.007, 0.023] | 0.013 [0.003, 0.022]c | 0.0001 [-0.0001, 0.0002] | - | 0.0001 [0.00003, 0.0002] | - |